Primary bone cancer – Primary bone cancers : osteosarcoma, chondrosarcoma, Ewing’s sarcoma

  • Is a rare disease (< 0,2% of all new cancer cases)
  • 2500 – 3000 new cases in Europe each year
  • Affects a young population (43% of cases are under 34)
  • 5-years survival rate of primary bone cancers is less than 60%
  • Metastatic disease has a poor prognostic (5-years survival <30%)

 

Bone metastases

  • Bone is one of the most common site of cancer spreading – affects 1,5 million cancer patients worldwide
  • Metastases to the bone are mostly incurable
Type of cancer Bone metastases incidence (%)
Myeloma 75-100
Prostate 65-75
Breast 65-75
Thyroid 60
Melanoma 15-45
Bladder 40
Lung & bronchus 30-40
Renal 20-25

Source: Coleman RE.Cancer Treat Rev 2001; 27: 165–176

 

Other indications pain, inflammation…

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